Target
Protein Tat
Ligand
BDBM50045400
Substrate
n/a
Meas. Tech.
ChEBML_209908
IC50
2600±n/a nM
Citation
 Michne, WFSchroeder, JDBailey, TRYoung, DCHughes, JVDutko, FJ Keto/enol epoxy steroids: a new structural class of HIV-1 Tat inhibitors. J Med Chem 36:2701-2 (1993) [PubMed]  Article 
Target
Name:
Protein Tat
Synonyms:
Human immunodeficiency virus type 1 Tat protein | Protein Tat | TAT_HV112 | Transactivating regulatory protein | tat
Type:
PROTEIN
Mol. Mass.:
9771.75
Organism:
Human immunodeficiency virus type 1 (isolate PCV12 group M subtype B)(HIV-1)
Description:
ChEMBL_199318
Residue:
86
Sequence:
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAPQGSQTHQVSLSKQPTSQSRGDPTGPKE
  
Inhibitor
Name:
BDBM50045400
Synonyms:
Acetic acid 2-methanesulfonyl-10,13-dimethyl-3-oxo-hexadecahydro-20-oxa-cyclopropa[4,5]cyclopenta[a]phenanthren-17-yl ester | CHEMBL3137861
Type:
Small organic molecule
Emp. Form.:
C22H32O6S
Mol. Mass.:
424.551
SMILES:
[H][C@@]12CC[C@H](OC(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]23OC2C(=O)C(C[C@]13C)S(C)(=O)=O
Structure:
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