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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50046615
Substrate
n/a
Meas. Tech.
ChEMBL_588 (CHEMBL615458)
Ki
1.8±n/a nM
Citation
 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; VonVoigtlander, PF; Chidester, CG Centrally acting serotonergic agents. Synthesis and structure-activity relationships of C-1- or C-3-substituted derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin. J Med Chem 36:671-82 (1993) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50046615
Synonyms:
(1-Allyl-8-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine | CHEMBL158791
Type:
Small organic molecule
Emp. Form.:
C17H25NO
Mol. Mass.:
259.3865
SMILES:
CCCN[C@@H]1CCc2cccc(OC)c2[C@@H]1CC=C
Structure:
Search PDB for entries with ligand similarity: