Reaction Details Report a problem with these data
Target
Transmembrane domain-containing protein TMIGD3
Ligand
BDBM50500113
Substrate
n/a
Meas. Tech.
ChEMBL_1546516 (CHEMBL3749019)
Ki
1.2±n/a nM
Citation
 Tosh, DK; Paoletta, S; Chen, Z; Crane, S; Lloyd, J; Gao, ZG; Gizewski, ET; Auchampach, JA; Salvemini, D; Jacobson, KA Structure-Based Design, Synthesis by Click Chemistry and  Medchemcomm 6:555-563[PubMed]  Article 
Target
Name:
Transmembrane domain-containing protein TMIGD3
Synonyms:
TMIG3_HUMAN | TMIGD3 | Transmembrane domain-containing protein TMIGD3
Type:
PROTEIN
Mol. Mass.:
30335.79
Organism:
Homo sapiens (Human)
Description:
ChEMBL_114868
Residue:
266
Sequence:
MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM
  
Inhibitor
Name:
BDBM50500113
Synonyms:
CHEMBL3747461
Type:
Small organic molecule
Emp. Form.:
C15H19IN6O3
Mol. Mass.:
458.2542
SMILES:
[H][C@]12C[C@]1([C@@H](O)[C@@H](O)[C@@H]2n1cnc2c(NCC)nc(I)nc12)C(=O)NC |r|
Structure:
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