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Target
Histamine H3 receptor
Ligand
BDBM22916
Substrate
n/a
Meas. Tech.
ChEMBL_83829 (CHEMBL692770)
Ki
5±n/a nM
Citation
 Stark, H; Purand, K; Hüls, A; Ligneau, X; Garbarg, M; Schwartz, JC; Schunack, W [125I]iodoproxyfan and related compounds: a reversible radioligand and novel classes of antagonists with high affinity and selectivity for the histamine H3 receptor. J Med Chem 39:1220-6 (1996) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
  
Inhibitor
Name:
BDBM22916
Synonyms:
5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole | CHEMBL19010 | Iodoproxyfan
Type:
Small organic molecule
Emp. Form.:
C13H15IN2O
Mol. Mass.:
342.1755
SMILES:
Ic1ccc(COCCCc2cnc[nH]2)cc1
Structure:
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