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Target
Mu-type opioid receptor
Ligand
BDBM50051177
Substrate
n/a
Meas. Tech.
ChEMBL_146987 (CHEMBL757525)
IC50
290±n/a nM
Citation
 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ Design, synthesis, and biological activities of cyclic lactam peptide analogues of dynorphine A(1-11)-NH2. J Med Chem 39:1136-41 (1996) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50051177
Synonyms:
CHEMBL264733 | Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2
Type:
Small organic molecule
Emp. Form.:
C65H106N20O14
Mol. Mass.:
1391.6627
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O
Structure:
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