Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50051342
Substrate
n/a
Meas. Tech.
ChEMBL_31838 (CHEMBL641515)
Ki
561.0±n/a nM
Citation
 Karton, Y; Jiang, JL; Ji, XD; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. J Med Chem 39:2293-301 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50051342
Synonyms:
3,6-Dichloro-2-(2-isobutoxy-4-methyl-phenyl)-chromen-4-one | CHEMBL307459
Type:
Small organic molecule
Emp. Form.:
C20H18Cl2O3
Mol. Mass.:
377.261
SMILES:
CC(C)COc1cc(C)ccc1-c1oc2ccc(Cl)cc2c(=O)c1Cl
Structure:
Search PDB for entries with ligand similarity: