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Target
Adenosine receptor A3
Ligand
BDBM50049387
Substrate
n/a
Meas. Tech.
ChEMBL_31838 (CHEMBL641515)
Ki
3400±n/a nM
Citation
 Karton, Y; Jiang, JL; Ji, XD; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. J Med Chem 39:2293-301 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50049387
Synonyms:
5,4'-Dihydroxy-7-o-methoxyflavanone | 5-Hydroxy-2-(4-hydroxy-phenyl)-7-methoxy-chroman-4-one | 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychroman-4-one | CHEMBL74852 | NSC-407228
Type:
Small organic molecule
Emp. Form.:
C16H14O5
Mol. Mass.:
286.2794
SMILES:
COc1cc(O)c2C(=O)CC(Oc2c1)c1ccc(O)cc1
Structure:
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