Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50051345
Substrate
n/a
Meas. Tech.
ChEMBL_31838 (CHEMBL641515)
Ki
45500±n/a nM
Citation
 Karton, Y; Jiang, JL; Ji, XD; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. J Med Chem 39:2293-301 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50051345
Synonyms:
4-Ethoxy-7-((1E,3E)-4-phenyl-buta-1,3-dienyl)-furo[3,2-g]chromen-5-one | CHEMBL78326
Type:
Small organic molecule
Emp. Form.:
C23H18O4
Mol. Mass.:
358.3866
SMILES:
CCOc1c2ccoc2cc2oc(\C=C\C=C\c3ccccc3)cc(=O)c12
Structure:
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