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Target
D(4) dopamine receptor
Ligand
BDBM50040245
Substrate
n/a
Meas. Tech.
ChEMBL_60979 (CHEMBL671597)
Ki
21±n/a nM
Citation
 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW (S)-(-)-4-[4-[2-(isochroman-1-yl)ethyl]-piperazin-1-yl] benzenesulfonamide, a selective dopamine D4 antagonist. J Med Chem 39:2435-7 (1996) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41307.65
Organism:
RAT
Description:
DOPAMINE D4.4 0 RAT::P30729
Residue:
387
Sequence:
MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASERILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVCCLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRKRGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
  
Inhibitor
Name:
BDBM50040245
Synonyms:
8-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine | CHEMBL63329
Type:
Small organic molecule
Emp. Form.:
C18H21N5
Mol. Mass.:
307.3928
SMILES:
CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(C)cc12 |t:8|
Structure:
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