Target
Translocator protein
Ligand
BDBM50054127
Substrate
n/a
Meas. Tech.
ChEMBL_39466 (CHEMBL653041)
IC50
3.9±n/a nM
Citation
 Anzini, MCappelli, AVomero, SGiorgi, GLanger, TBruni, GRomeo, MRBasile, AS Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem. J Med Chem 39:4275-84 (1996) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:
Mitochondrion membrane protein
Mol. Mass.:
18945.84
Organism:
Rattus norvegicus (rat)
Description:
Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:
169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
  
Inhibitor
Name:
BDBM50054127
Synonyms:
2-[6-Chloro-2-(4-chloro-phenyl)-1,8a-dihydro-imidazo[1,2-a]pyridin-3-yl]-N,N-dipropyl-acetamide | CHEMBL137689
Type:
Small organic molecule
Emp. Form.:
C21H25Cl2N3O
Mol. Mass.:
406.349
SMILES:
CCCN(CCC)C(=O)CC1N2C=C(Cl)C=CC2N=C1c1ccc(Cl)cc1 |c:15,19,t:12|
Structure:
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