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Target
D(2) dopamine receptor
Ligand
BDBM50036862
Substrate
n/a
Meas. Tech.
ChEMBL_59317 (CHEMBL670211)
IC50
50.0±n/a nM
Citation
 Comoy, C; Marot, C; Podona, T; Baudin, ML; Morin-Allory, L; Guillaumet, G; Pfeiffer, B; Caignard, DH; Renard, P; Rettori, MC; Adam, G; Guardiola-Lemaitre, B 3-amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans] J Med Chem 39:4285-98 (1996) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50036862
Synonyms:
(5-Methoxy-chroman-3-yl)-dipropyl-amine | CHEMBL283606
Type:
Small organic molecule
Emp. Form.:
C16H25NO2
Mol. Mass.:
263.3752
SMILES:
CCCN(CCC)C1COc2cccc(OC)c2C1
Structure:
Search PDB for entries with ligand similarity: