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Target
Adenosylhomocysteinase
Ligand
BDBM50408389
Substrate
n/a
Meas. Tech.
ChEMBL_196559 (CHEMBL801953)
IC50
>500000±n/a nM
Citation
 Seley, KL; Schneller, SW; Rattendi, D; Bacchi, CJ (+)-7-Deaza-5'-noraristeromycin as an anti-trypanosomal agent. J Med Chem 40:622-4 (1997) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
Adenosylhomocysteinase | AdoHcyase | Ahcy | CUBP | Liver copper-binding protein | S-adenosyl-L-homocysteine hydrolase | SAHH_MOUSE
Type:
PROTEIN
Mol. Mass.:
47687.65
Organism:
Mus musculus
Description:
ChEMBL_196559
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY
  
Inhibitor
Name:
BDBM50408389
Synonyms:
CHEMBL2051757
Type:
Small organic molecule
Emp. Form.:
C11H14N4O3
Mol. Mass.:
250.2539
SMILES:
Nc1ncnc2n(ccc12)[C@H]1C[C@@H](O)[C@H](O)[C@@H]1O |r|
Structure:
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