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TargetD(2) dopamine receptor
LigandBDBM50020680
Substrate/Competitorn/a
Meas. Tech.ChEMBL_61124
Ki 7.2±n/a nM
Citation Heier, RFDolak, LADuncan, JNHyslop, DKLipton, MFMartin, IJMauragis, MAPiercey, MFNichols, NFSchreur, PJSmith, MWMoon, MW Synthesis and biological activities of (R)-5,6-dihydro-N,N-dimethyl-4H-imidazo[4,5,1-ij]quinolin-5-amine and its metabolites. J Med Chem40:639-46 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(2) dopamine receptor
Name:Dopamine receptor D2L/neurotensin receptor NTS1
Synonyms:DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like
Type:Cell-surface receptors
Mol. Mass.:50647.10
Organism:Homo sapiens (Human)
Description:P14416
Residue:443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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  Blast E-value cutoff:
BDBM50020680
NameBDBM50020680
Synonyms:4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one | CHEMBL589 | ROPINIROLE
TypeSmall organic molecule
Emp. Form.C16H24N2O
Mol. Mass.260.3746
SMILESCCCN(CCC)CCc1cccc2NC(=O)Cc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a