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Target
Programmed cell death 1 ligand 1
Ligand
BDBM50507500
Substrate
n/a
Meas. Tech.
ChEMBL_1830213 (CHEMBL4330221)
EC50
30±n/a nM
Citation
 Wang, T; Wu, X; Guo, C; Zhang, K; Xu, J; Li, Z; Jiang, S Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway. J Med Chem 62:1715-1730 (2019) [PubMed]  Article 
Target
Name:
Programmed cell death 1 ligand 1
Synonyms:
B7 homolog 1 | B7-H1 | B7h1 | CD_antigen=CD274 | Cd274 | PD-L1 | PD1L1_MOUSE | PDCD1 ligand 1 | Pdcd1l1 | Pdcd1lg1 | Pdl1 | Programmed cell death 1 ligand 1 | Programmed death ligand 1
Type:
PROTEIN
Mol. Mass.:
32778.59
Organism:
Mus musculus
Description:
ChEMBL_119198
Residue:
290
Sequence:
MRIFAGIIFTACCHLLRAFTITAPKDLYVVEYGSNVTMECRFPVERELDLLALVVYWEKEDEQVIQFVAGEEDLKPQHSNFRGRASLPKDQLLKGNAALQITDVKLQDAGVYCCIISYGGADYKRITLKVNAPYRKINQRISVDPATSEHELICQAEGYPEAEVIWTNSDHQPVSGKRSVTTSRTEGMLLNVTSSLRVNATANDVFYCTFWRSQPGQNHTAELIIPELPATHPPQNRTHWVLLGSILLFLIVVSTVLLFLRKQVRMLDVEKCGVEDTSSKNRNDTQFEET
  
Inhibitor
Name:
BDBM50507500
Synonyms:
CHEMBL4438020
Type:
Small organic molecule
Emp. Form.:
C12H22N6O8
Mol. Mass.:
378.3385
SMILES:
C[C@@H](O)[C@H](NC(=O)N[C@@H](CC(N)=O)C(=O)NNC(=O)[C@@H](N)CO)C(O)=O |r|
Structure:
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