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Target5-hydroxytryptamine receptor 1B
LigandBDBM50064820
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1350
Ki 3480±n/a nM
Citation Law, HDukat, MTeitler, MLee, DKMazzocco, LKamboj, RRampersad, VPrisinzano, TGlennon, RA Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation. J Med Chem41:2243-51 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1B
Name:Serotonin (5-HT) receptor
Synonyms:5-HT-1B | 5-HT-1D-beta | 5-HT1B | 5-hydroxytryptamine receptor 1B (5-HT1B) | S12 | Serotonin 1D beta receptor | Serotonin Receptor 1B
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:43579.17
Organism:Homo sapiens (Human)
Description:Receptor binding assays were performed using human clone stably expressed in CHO cells
Residue:390
Sequence:
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
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  Blast E-value cutoff:
BDBM50064820
NameBDBM50064820
Synonyms:2-(2,4,6-Trimethyl-benzyl)-4,5-dihydro-1H-imidazole | CHEMBL72178
TypeSmall organic molecule
Emp. Form.C13H18N2
Mol. Mass.202.2954
SMILESCc1cc(C)c(CC2=NCCN2)c(C)c1 |t:7|
Structure
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n/a