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Target
D(2) dopamine receptor
Ligand
BDBM50065578
Substrate
n/a
Meas. Tech.
ChEMBL_60973 (CHEMBL671591)
Ki
0.288±n/a nM
Citation
 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Synthesis and pharmacological characterization of novel 6-fluorochroman derivatives as potential 5-HT1A receptor antagonists. J Med Chem 41:2765-78 (1998) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50065578
Synonyms:
CHEMBL419147 | [2-(6-Fluoro-2H-chromen-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine
Type:
Small organic molecule
Emp. Form.:
C22H26FNO3
Mol. Mass.:
371.4451
SMILES:
COc1ccc(CCCCNCCOc2cc(F)cc3C=CCOc23)cc1 |c:20|
Structure:
Search PDB for entries with ligand similarity: