Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50067111
Substrate
n/a
Meas. Tech.
ChEMBL_31996 (CHEMBL646593)
Ki
96000±n/a nM
Citation
 van Muijlwijk-Koezen, JE; Timmerman, H; Link, R; van der Goot, H; Ijzerman, AP A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem 41:3994-4000 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50067111
Synonyms:
4-Methyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide | 4-methyl-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide | CHEMBL339261
Type:
Small organic molecule
Emp. Form.:
C22H17N3O
Mol. Mass.:
339.3899
SMILES:
Cc1ccc(cc1)C(=O)Nc1nc(cc2ccccc12)-c1ccccn1
Structure:
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