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Target
Leukotriene B4 receptor 1
Ligand
BDBM50072996
Substrate
n/a
Meas. Tech.
ChEMBL_99840 (CHEMBL706759)
Ki
9.5±n/a nM
Citation
 Greenspan, PD; Fujimoto, RA; Marshall, PJ; Raychaudhuri, A; Lipson, KE; Zhou, H; Doti, RA; Coppa, DE; Zhu, L; Pelletier, R; Uziel-Fusi, S; Jackson, RH; Chin, MH; Kotyuk, BL; Fitt, JJ Carboxy-substituted cinnamides: a novel series of potent, orally active LTB4 receptor antagonists. J Med Chem 42:164-72 (1999) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50072996
Synonyms:
3-[5-((E)-2-Diethylcarbamoyl-1-methyl-vinyl)-2-(1-phenyl-ethoxy)-phenyl]-propionic acid | CHEMBL49866
Type:
Small organic molecule
Emp. Form.:
C25H31NO4
Mol. Mass.:
409.5179
SMILES:
CCN(CC)C(=O)\C=C(/C)c1ccc(OC(C)c2ccccc2)c(CCC(O)=O)c1
Structure:
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