Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 4
Ligand
BDBM50073048
Substrate
n/a
Meas. Tech.
ChEMBL_143982 (CHEMBL857547)
IC50
>5000±n/a nM
Citation
 Kordik, CP; Reitz, AB Pharmacological treatment of obesity: therapeutic strategies. J Med Chem 42:181-201 (1999) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 4
Synonyms:
NPY-Y4 | NPY4-R | NPY4R_RAT | Neuropeptide Y receptor type 4 | Npy4r | PP1 | Pancreatic polypeptide receptor 1 | Ppyr1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42577.98
Organism:
RAT
Description:
NPY-Y4 PPYR1 RAT::Q63447
Residue:
375
Sequence:
MNTSHLMASLSPAFLQGKNGTNPLDSLYNLSDGCQDSADLLAFIITTYSVETVLGVLGNLCLIFVTTRQKEKSNVTNLLIANLAFSDFLMCLICQPLTVTYTIMDYWIFGEVLCKMLTFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVVIWFISCFLSLPFLANSILNDLFHYNHSKVVEFLEDKVVCFVSWSSDHHRLIYTTFLLLFQYCVPLAFILVCYMRIYQRLQRQRRAFHTHTCSSRVGQMKRINGMLMAMVTAFAVLWLPLHVFNTLEDWYQEAIPACHGNLIFLMCHLFAMASTCVNPFIYGFLNINFKKDIKALVLTCRCRPPQGEPEPLPLSTVHTDLSKGSMRMGSKSNVM
  
Inhibitor
Name:
BDBM50073048
Synonyms:
2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-N-(9-oxo-9H-fluoren-3-yl)-acetamide | CHEMBL62166
Type:
Small organic molecule
Emp. Form.:
C27H24N4O3
Mol. Mass.:
452.5045
SMILES:
O=C(CN1CCC(CC1)n1c2ccccc2[nH]c1=O)Nc1ccc2C(=O)c3ccccc3-c2c1
Structure:
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