Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50066626
Substrate
n/a
Meas. Tech.
ChEMBL_212508 (CHEMBL817573)
Ki
1100±n/a nM
Citation
 Phillips, G; Davey, DD; Eagen, KA; Koovakkat, SK; Liang, A; Ng, HP; Pinkerton, M; Trinh, L; Whitlow, M; Beatty, AM; Morrissey, MM Design, synthesis, and activity of 2,6-diphenoxypyridine-derived factor Xa inhibitors. J Med Chem 42:1749-56 (1999) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50066626
Synonyms:
3-{6-[3-amino(imino)methylphenoxy]-2-pyridyloxy}phenyl-iminomethanamine | CHEMBL50127
Type:
Small organic molecule
Emp. Form.:
C19H17N5O2
Mol. Mass.:
347.3706
SMILES:
NC(=N)c1cccc(Oc2cccc(Oc3cccc(c3)C(N)=N)n2)c1
Structure:
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