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Target
Acyl-CoA:cholesterol acyltransferase
Ligand
BDBM50079715
Substrate
n/a
Meas. Tech.
ChEMBL_28179 (CHEMBL638585)
IC50
6±n/a nM
Citation
 Matsuyama, N; Kosaka, T; Fukuhara, M; Soda, Y; Mizuno, K Polyunsaturated fatty acid anilides as inhibitors of acyl-coA: cholesterol acyltransferase (ACAT). Bioorg Med Chem Lett 9:2039-42 (1999) [PubMed]  Article 
Target
Name:
Acyl-CoA:cholesterol acyltransferase
Synonyms:
ACAT
Type:
n/a
Mol. Mass.:
35405.31
Organism:
Oryctolagus cuniculus
Description:
n/a
Residue:
305
Sequence:
PLFLKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILKEMKNNHRAKDLRAPPEQGKIFVARRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFNLLSYAFGKLPTVVWTWWTMFLSTLSIPYFLFQHWANGYSKSSHPLMYSLFHGLLFMVFQLGILGFGPTYIVLAYTLPPASRFIVILEQIRLIMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFAQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCIF
  
Inhibitor
Name:
BDBM50079715
Synonyms:
CHEMBL64237 | Tetradecanethioic acid (2,6-diisopropyl-phenyl)-amide
Type:
Small organic molecule
Emp. Form.:
C26H45NS
Mol. Mass.:
403.707
SMILES:
CCCCCCCCCCCCCC(=S)Nc1c(cccc1C(C)C)C(C)C
Structure:
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