Target
H2-K region expressed gene 2, rat orthologue
Ligand
BDBM50079821
Substrate
n/a
Meas. Tech.
ChEBML_103872
IC50
3000±n/a nM
Citation
 Jones, ABActon, JJRivetna, MNCummings, RTCubbon, RMNichols, EASchwartz, CDWicker, LSHermes, JD Tetrapeptide derived inhibitors of complexation of a class II MHC: the peptide backbone is not inviolate. Bioorg Med Chem Lett 9:2109-14 (1999) [PubMed]  Article 
Target
Name:
H2-K region expressed gene 2, rat orthologue
Synonyms:
MHC class II | MHC class II region expressed gene KE2, isoform CRA_a
Type:
PROTEIN
Mol. Mass.:
14499.39
Organism:
Rattus norvegicus
Description:
ChEMBL_10342
Residue:
127
Sequence:
MAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQNAKAPGKA
  
Inhibitor
Name:
BDBM50079821
Synonyms:
(1-(S)-1-Benzyl-2-{1-[(S)-1-((S)-1-carbamoyl-3-methyl-butylcarbamoyl)-butylcarbamoyl]-4-guanidino-butylamino}-ethyl)-carbamic acid ethyl ester | CHEMBL64985
Type:
Small organic molecule
Emp. Form.:
C29H50N8O5
Mol. Mass.:
590.7579
SMILES:
CCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC[C@H](Cc1ccccc1)NC(=O)OCC)C(=O)N[C@@H](CC(C)C)C(N)=O
Structure:
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