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Target
Sodium-dependent phosphate transport protein 1
Ligand
BDBM50081123
Substrate
n/a
Meas. Tech.
ChEBML_72010
Ki
204000±n/a nM
Citation
 Carrigan, CN; Esslinger, CS; Bartlett, RD; Bridges, RJ; Thompson, CM Quinoline-2,4-dicarboxylic acids: synthesis and evaluation as inhibitors of the glutamate vesicular transport system. Bioorg Med Chem Lett 9:2607-12 (1999) [PubMed]  Article 
Target
Name:
Sodium-dependent phosphate transport protein 1
Synonyms:
NPT1_RAT | Na(+)/PI cotransporter 1 | Npt1 | Renal Na(+)-dependent phosphate cotransporter 1 | Renal sodium-dependent phosphate transport protein 1 | Renal sodium-phosphate transport protein 1 | Slc17a1 | Sodium-dependent phosphate transport protein 1 | Sodium/phosphate cotransporter 1 | Solute carrier family 17 member 1
Type:
PROTEIN
Mol. Mass.:
51362.55
Organism:
Rattus norvegicus
Description:
ChEMBL_72010
Residue:
465
Sequence:
MENRCLPKKVPGFCSFRYGLAILLHFCNIVIMAQRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKNPVHSWSLDIQGLVLSSVFLGMVVIQVPVGYLSGAYPMEKIIGSSLFLSSVLSLLIPPAAQVGAALVIVCRVLQGIAQGAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFICDLLGWPMVFYIFGIVGCVLSLFWFILLFDDPNNHPYMSSSEKDYITSSLMQQVHSGRQSLPIKAMLKSLPLWAIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSRKIFSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYSTVIFLTLANSTLSFSFCGQLINALDIAPRYYGFLKAVTALIGIFGGLISSTLAGLILNQDPEYAWHKNFFLMAGINVTCLAFYLLFAKGDIQDWAKETKTTRL
  
Inhibitor
Name:
BDBM50081123
Synonyms:
6-Benzyloxy-quinoline-2,4-dicarboxylic acid | CHEMBL73304
Type:
Small organic molecule
Emp. Form.:
C18H13NO5
Mol. Mass.:
323.2995
SMILES:
OC(=O)c1cc(C(O)=O)c2cc(OCc3ccccc3)ccc2n1
Structure:
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