Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50081669
Substrate
n/a
Meas. Tech.
ChEMBL_29889 (CHEMBL641960)
Ki
1350±n/a nM
Citation
 Xie, R; Li, AH; Ji, XD; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Selective A(3) adenosine receptor antagonists: water-soluble 3, 5-diacyl-1,2,4-trialkylpyridinium salts and their oxidative generation from dihydropyridine precursors. J Med Chem 42:4232-8 (1999) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50081669
Synonyms:
3-Ethoxycarbonyl-4,6-diethyl-5-ethylsulfanylcarbonyl-2-phenyl-1-propyl-pyridinium; iodide | CHEMBL336629
Type:
Small organic molecule
Emp. Form.:
C24H32NO3S
Mol. Mass.:
414.58
SMILES:
CCC[n+]1c(CC)c(C(=O)SCC)c(CC)c(C(=O)OCC)c1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: