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Target
Adenosine receptor A3
Ligand
BDBM50084019
Substrate
n/a
Meas. Tech.
ChEBML_31409
Ki
1300±n/a nM
Citation
 Webb, TR; Melman, N; Lvovskiy, D; Ji, XD; Jacobson, KA The utilization of a unified pharmacophore query in the discovery of new antagonists of the adenosine receptor family. Bioorg Med Chem Lett 10:31-4 (2000) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50084019
Synonyms:
6,7-Dimethoxy-3-[4-(4-methoxy-phenyl)-thiazol-2-ylamino]-3H-isobenzofuran-1-one | CHEMBL114643
Type:
Small organic molecule
Emp. Form.:
C20H18N2O5S
Mol. Mass.:
398.432
SMILES:
COc1ccc(cc1)-c1csc(NC2OC(=O)c3c2ccc(OC)c3OC)n1
Structure:
Search PDB for entries with ligand similarity: