Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50532777
Substrate
n/a
Meas. Tech.
ChEMBL_1923902 (CHEMBL4426858)
Ki
0.100000±n/a nM
Citation
 Kulkarni, S; Nikas, SP; Sharma, R; Jiang, S; Paronis, CA; Leonard, MZ; Zhang, B; Honrao, C; Mallipeddi, S; Raghav, JG; Benchama, O; Järbe, TU; Bergman, J; Makriyannis, A Novel C-Ring-Hydroxy-Substituted Controlled Deactivation Cannabinergic Analogues. J Med Chem 59:6903-19 (2016) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50532777
Synonyms:
CHEMBL4470925
Type:
Small organic molecule
Emp. Form.:
C24H36O5
Mol. Mass.:
404.5396
SMILES:
[H][C@@]12C[C@H](CO)CC[C@@]1([H])C(C)(C)Oc1cc(cc(O)c21)C(C)(C)C(=O)OCCCC |r|
Structure:
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