Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50088954
Substrate
n/a
Meas. Tech.
ChEBML_212533
Ki
10±n/a nM
Citation
 Zhao, Z; Arnaiz, DO; Griedel, B; Sakata, S; Dallas, JL; Whitlow, M; Trinh, L; Post, J; Liang, A; Morrissey, MM; Shaw, KJ Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors. Bioorg Med Chem Lett 10:963-6 (2000) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50088954
Synonyms:
7-{2-sec-Butyl-6-[1-(1-imino-ethyl)-piperidin-4-yloxy]-benzoimidazol-1-ylmethyl}-naphthalene-2-carboxamidine | CHEMBL369165
Type:
Small organic molecule
Emp. Form.:
C30H36N6O
Mol. Mass.:
496.6464
SMILES:
CCC(C)c1nc2ccc(OC3CCN(CC3)C(C)=N)cc2n1Cc1ccc2ccc(cc2c1)C(N)=N
Structure:
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