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Reaction Details
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TargetTrypsin
LigandBDBM50088943
Substrate/Competitorn/a
Meas. Tech.ChEBML_212533
Ki 8.2±n/a nM
Citation Zhao, ZArnaiz, DOGriedel, BSakata, SDallas, JLWhitlow, MTrinh, LPost, JLiang, AMorrissey, MMShaw, KJ Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors. Bioorg Med Chem Lett10:963-6 (2000) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Trypsin
Name:Trypsin I
Synonyms:Beta-Trypsin | Cationic trypsin | Trypsin I
Type:Enzyme
Mol. Mass.:25790.52
Organism:Bos taurus (bovine)
Description:P00760
Residue:246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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BDBM50088943
NameBDBM50088943
Synonyms:7-{5-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-benzoimidazol-1-ylmethyl}-naphthalene-2-carboxamidine | CHEMBL172378
TypeSmall organic molecule
Emp. Form.C26H28N6O
Mol. Mass.440.5401
SMILESCC(=N)N1CCC(CC1)Oc1ccc2n(Cc3ccc4ccc(cc4c3)C(N)=N)cnc2c1
Structure
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