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Target
Prostaglandin F2-alpha receptor
Ligand
BDBM50090132
Substrate
n/a
Meas. Tech.
ChEMBL_157958 (CHEMBL766820)
IC50
210±n/a nM
Citation
 deLong, MA; Amburgey, J; Taylor, C; Wos, JA; Soper, DL; Wang, Y; Hicks, R Synthesis and in vitro evaluation of human FP-receptor selective prostaglandin analogues. Bioorg Med Chem Lett 10:1519-22 (2000) [PubMed]  Article 
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor
Type:
Enzyme
Mol. Mass.:
40072.29
Organism:
Homo sapiens (Human)
Description:
P43088
Residue:
359
Sequence:
MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
  
Inhibitor
Name:
BDBM50090132
Synonyms:
7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Cyano-phenyl)-3-hydroxy-pentyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid | CHEMBL286132
Type:
Small organic molecule
Emp. Form.:
C24H35NO5
Mol. Mass.:
417.5384
SMILES:
O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C#N
Structure:
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