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TargetAdenosine kinase
LigandBDBM50090886
Substrate/Competitorn/a
Meas. Tech.ChEMBL_31116
IC50 775±n/a nM
Citation Ugarkar, BGCastellino, AJDaRe, JMKopcho, JJWiesner, JBSchanzer, JMErion, MD Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues. J Med Chem43:2894-905 (2000) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine kinase
Name:Adenosine kinase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:40545.97
Organism:Homo sapiens (Human)
Description:ChEMBL_1467841
Residue:362
Sequence:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAED
KHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKA
AEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKAR
VCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGN
ETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFA
VLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD
FH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50090886
NameBDBM50090886
Synonyms:2-[5-Iodo-4-(4-methoxy-phenylamino)-pyrrolo[2,3-d]pyrimidin-7-yl]-5-methyl-tetrahydro-furan-3,4-diol | CHEMBL98887
TypeSmall organic molecule
Emp. Form.C18H19IN4O4
Mol. Mass.482.2723
SMILESCOc1ccc(Nc2ncnc3n(cc(I)c23)[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a