Target
Melatonin receptor type 1B
Ligand
BDBM50093267
Substrate
n/a
Meas. Tech.
ChEMBL_105244 (CHEMBL712574)
Ki
0.31±n/a nM
Citation
 Jellimann, CMathé-Allainmat, MAndrieux, JKloubert, SBoutin, JANicolas, JPBennejean, CDelagrange, PLanglois, M Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors. J Med Chem 43:4051-62 (2000) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50093267
Synonyms:
CHEMBL334962 | Cyclopropanecarboxylic acid (8-methoxy-acenaphthen-1-ylmethyl)-amide
Type:
Small organic molecule
Emp. Form.:
C18H19NO2
Mol. Mass.:
281.349
SMILES:
COc1ccc2cccc3CC(CNC(=O)C4CC4)c1c23
Structure:
Search PDB for entries with ligand similarity: