Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM50093262
Substrate
n/a
Meas. Tech.
ChEMBL_105244 (CHEMBL712574)
Ki
0.069±n/a nM
Citation
 Jellimann, C; Mathé-Allainmat, M; Andrieux, J; Kloubert, S; Boutin, JA; Nicolas, JP; Bennejean, C; Delagrange, P; Langlois, M Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors. J Med Chem 43:4051-62 (2000) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50093262
Synonyms:
CHEMBL131252 | N-(9-Methoxy-2,3-dihydro-1H-phenalen-1-ylmethyl)-butyramide
Type:
Small organic molecule
Emp. Form.:
C19H23NO2
Mol. Mass.:
297.3914
SMILES:
CCCC(=O)NCC1CCc2cccc3ccc(OC)c1c23
Structure:
Search PDB for entries with ligand similarity: