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TargetIsocitrate lyase
LigandBDBM50537899
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1971676
IC50 11000±n/a nM
Citation Bae, JCho, EPark, JSWon, THSeo, SYOh, DCOh, KBShin, J Isocadiolides A-H: Polybrominated Aromatics from a  J Nat Prod83:429-437 (2020) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Isocitrate lyase
Name:Isocitrate lyase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:61398.95
Organism:Candida albicans
Description:ChEMBL_972063
Residue:550
Sequence:
MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQA
DKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLA
DYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGI
TAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGS
NLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIE
SEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGK
DIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKA
AVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSN
QYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTE
DQFKESKAKA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50537899
NameBDBM50537899
Synonyms:CADIOLIDE D | Cadiolide D
TypeSmall organic molecule
Emp. Form.C24H11Br5O6
Mol. Mass.794.861
SMILESOc1ccc(\C=C2/OC(=O)C(C(=O)c3cc(Br)c(O)c(Br)c3)=C2c2cc(Br)c(O)c(Br)c2)cc1Br |c:22|
Structure
n/a