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Target5-hydroxytryptamine receptor 1A (5-HT1A)
LigandBDBM50097891
Substrate/Competitorn/a
Meas. Tech.ChEBML_897
Ki 0.120000±n/a nM
Citation Laban, UKurrasch-Orbaugh, DMarona-Lewicka, DNichols, DE A novel fluorinated tryptamine with highly potent serotonin 5-HT1A receptor agonist properties. Bioorg Med Chem Lett11:793-5 (2001) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1A (5-HT1A)
Name:5-hydroxytryptamine receptor 1A (5-HT1A)
Synonyms:5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:n/a
Mol. Mass.:46122.49
Organism:Homo sapiens (Human)
Description:n/a
Residue:422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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  Blast E-value cutoff:
BDBM50097891
NameBDBM50097891
Synonyms:4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole | CHEMBL352186
TypeSmall organic molecule
Emp. Form.C15H19FN2O
Mol. Mass.262.3226
SMILESCOc1ccc2[nH]cc(CCN3CCCC3)c2c1F
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a