Target
Cathepsin G
Ligand
BDBM50541448
Substrate
n/a
Meas. Tech.
ChEMBL_1984307 (CHEMBL4617713)
IC50
666000±n/a nM
Citation
 Hecker, SJReddy, KRLomovskaya, OGriffith, DCRubio-Aparicio, DNelson, KTsivkovski, RSun, DSabet, MTarazi, ZParkinson, JTotrov, MBoyer, SHGlinka, TWPemberton, OAChen, YDudley, MN Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-?-lactamases. J Med Chem 63:7491-7507 (2020) [PubMed]  Article 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50541448
Synonyms:
CHEMBL4633785
Type:
Small organic molecule
Emp. Form.:
C10H8BFO4
Mol. Mass.:
221.978
SMILES:
[H][C@@]12C[C@]1([H])c1ccc(F)c(C(O)=O)c1OB2O |r|
Structure:
Search PDB for entries with ligand similarity: