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Target
D(3) dopamine receptor
Ligand
BDBM50099814
Substrate
n/a
Meas. Tech.
ChEMBL_62749 (CHEMBL674590)
Ki
1.6±n/a nM
Citation
 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Synthesis and structure-activity relationships of naphthamides as dopamine D3 receptor ligands. J Med Chem 44:1815-26 (2001) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3
Type:
Protein
Mol. Mass.:
49540.58
Organism:
Rattus norvegicus (Rat)
Description:
P19020
Residue:
446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50099814
Synonyms:
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide | 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-3-yl)-amide | CHEMBL298875
Type:
Small organic molecule
Emp. Form.:
C23H23BrN2O2
Mol. Mass.:
439.345
SMILES:
COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1
Structure:
Search PDB for entries with ligand similarity: