Reaction Details Report a problem with these data
Target
Calpain small subunit 1
Ligand
BDBM50093805
Substrate
n/a
Meas. Tech.
ChEBML_43685
Ki
72.0±n/a nM
Citation
 Donkor, IO; Zheng, X; Han, J; Lacy, C; Miller, DD Significance of hydrogen bonding at the S(1)' subsite of calpain I. Bioorg Med Chem Lett 11:1753-5 (2001) [PubMed]  Article 
Target
Name:
Calpain small subunit 1
Synonyms:
CANP small subunit | CAPN4 | CAPNS1 | CDPS | CPNS1_PIG | CSS1 | Calcium-activated neutral proteinase small subunit | Calcium-dependent protease small subunit | Calcium-dependent protease small subunit 1 | Calpain regulatory subunit
Type:
PROTEIN
Mol. Mass.:
28062.13
Organism:
Sus scrofa
Description:
ChEMBL_43862
Residue:
266
Sequence:
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKQFDVDRSGTIGSSELPGAFEAAGFHLNEHLYSMIIRRYSDEGGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
  
Inhibitor
Name:
BDBM50093805
Synonyms:
CHEMBL416281 | [(S)-1-((S)-1-Benzyl-2-oxo-2-phenethylcarbamoyl-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester
Type:
Small organic molecule
Emp. Form.:
C32H37N3O5
Mol. Mass.:
543.6533
SMILES:
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)NCCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: