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Target5-hydroxytryptamine receptor 3A
LigandBDBM50103076
Substrate/Competitorn/a
Meas. Tech.ChEMBL_3480
Ki 1.4±n/a nM
Citation Parihar, HSSuryanarayanan, AMa, CJoshi, PVenkataraman, PSchulte, MKKirschbaum, KS 5-HT(3)R binding of lerisetron: an interdisciplinary approach to drug-Receptor interactions. Bioorg Med Chem Lett11:2133-6 (2001) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 3A
Name:Serotonin 3 (5-HT3) receptor
Synonyms:5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3
Type:Protein
Mol. Mass.:55283.27
Organism:Homo sapiens (Human)
Description:P46098
Residue:478
Sequence:
MLLWVQQALLALLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTT
VSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDI
LINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH
TIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRR
RPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAI
GTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQ
STSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQ
ELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA
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BDBM50103076
NameBDBM50103076
Synonyms:1-Naphthalen-2-ylmethyl-2-piperazin-1-yl-1H-benzoimidazole | CHEMBL63863
TypeSmall organic molecule
Emp. Form.C22H22N4
Mol. Mass.342.4369
SMILESC(c1ccc2ccccc2c1)n1c(nc2ccccc12)N1CCNCC1
Structure
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n/a