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TargetFibroblast growth factor 23
LigandBDBM50549233
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2024190
IC50 200±n/a nM
Citation Downs, RP; Xiao, Z; Ikedionwu, MO; Cleveland, JW; Lin Chin, A; Cafferty, AE; Darryl Quarles, L; Carrick, JD Design and development of FGF-23 antagonists: Definition of the pharmacophore and initial structure-activity relationships probed by synthetic analogues. Bioorg Med Chem29:0 (2021) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Fibroblast growth factor 23
Name:Fibroblast growth factor 23
Synonyms:FGF-23 | FGF23 | Fibroblast growth factor 23 | Fibroblast growth factor 23 C-terminal peptide | Fibroblast growth factor 23 N-terminal peptide | HYPF | Phosphatonin | Tumor-derived hypophosphatemia-inducing factor
Type:PROTEIN
Mol. Mass.:27966.65
Organism:Homo sapiens
Description:ChEMBL_115874
Residue:251
Sequence:
MLGARLRLWVCALCSVCSMSVLRAYPNASPLLGSSWGGLIHLYTATARNSYHLQIHKNGH
VDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENCRFQHQTL
ENGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHFNTPIPRRHTRS
AEDDSERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVRGGRVNTHAGGTG
PEGCRPFAKFI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50549233
NameBDBM50549233
Synonyms:CHEMBL4790497
TypeSmall organic molecule
Emp. Form.C15H17NO
Mol. Mass.227.3016
SMILESCc1ccc(\C=C\C2=C(CCC2)/C=N/O)cc1 |t:7|
Structure
n/a