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Target
Cereblon isoform 4
Ligand
BDBM50026472
Substrate
n/a
Meas. Tech.
ChEMBL_2025844 (CHEMBL4679657)
IC50
20800±n/a nM
Citation
 Maiwald, S; Heim, C; Hernandez Alvarez, B; Hartmann, MD Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay. ACS Med Chem Lett 12:74-81 (2021) [PubMed]  Article 
Target
Name:
Cereblon isoform 4
Synonyms:
Cereblon isoform 4
Type:
PROTEIN
Mol. Mass.:
13620.40
Organism:
Magnetospirillum gryphiswaldense
Description:
ChEMBL_116733
Residue:
124
Sequence:
MPLDAGGQNSTQMVLAPGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRLIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLAEGPAD
  
Inhibitor
Name:
BDBM50026472
Synonyms:
(CH3)2SO | (methanesulfinyl)methanedimethyl sulfoxide | CHEMBL504 | DIMETHYL SULFOXIDE | Dimethylsulfoxid | S(O)Me2 | US11866416, Compound DMSO | dimethyl sulfur oxide | dimethyl sulphoxide | dmso | methylsulfinylmethane | sulfinylbis(methane)
Type:
Small organic molecule
Emp. Form.:
C2H6OS
Mol. Mass.:
78.133
SMILES:
CS(C)=O
Structure:
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