Reaction Details
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Adenosine receptor A3
Ligand
BDBM50451378
Substrate
n/a
Meas. Tech.
ChEBML_30634
EC50
0.000±n/a nM
Comments
From 0.00000100 on 20220115
Citation
Chordia, MD; Murphree, LJ; Macdonald, TL; Linden, J; Olsson, RA 2-Aminothiazoles: a new class of agonist allosteric enhancers of A(1) adenosine receptors. Bioorg Med Chem Lett 12:1563-6 (2002) [PubMed] Article More Info.:
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
Inhibitor
Name:
BDBM50451378
Synonyms:
CHEMBL39106
Type:
Small organic molecule
Emp. Form.:
C13H13IN2O2S
Mol. Mass.:
388.224
SMILES:
I.CC(=O)Oc1ccc2-c3nc(N)sc3CCc2c1
Structure:
