Reaction Details Report a problem with these data
Target
Matrix metalloproteinase-9
Ligand
BDBM50116273
Substrate
n/a
Meas. Tech.
ChEBML_71659
IC50
48000±n/a nM
Citation
 Wang, X; Choe, Y; Craik, CS; Ellman, JA Design and synthesis of novel inhibitors of gelatinase B. Bioorg Med Chem Lett 12:2201-4 (2002) [PubMed]  Article 
Target
Name:
Matrix metalloproteinase-9
Synonyms:
92 kDa gelatinase | 92 kDa type IV collagenase | Clg4b | GELB | Gelatinase B | MMP-9 | MMP9_MOUSE | Matrix metalloproteinase 9 | Matrix metalloproteinase-9 | Mmp9
Type:
PROTEIN
Mol. Mass.:
80529.41
Organism:
Mus musculus
Description:
ChEMBL_71659
Residue:
730
Sequence:
MSPWQPLLLALLAFGCSSAAPYQRQPTFVVFPKDLKTSNLTDTQLAEAYLYRYGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGELDSQTLKAIRTPRCGVPDVGRFQTFKGLKWDHHNITYWIQNYSEDLPRDMIDDAFARAFAVWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGAGVQGDAHFDDDELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDGKFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWCATTANYDQDKLYGFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKDDIDGIQYLYGRGSKPDPRPPATTTTEPQPTAPPTMCPTIPPTAYPTVGPTVGPTGAPSPGPTSSPSPGPTGAPSPGPTAPPTAGSSEASTESLSPADNPCNVDVFDAIAEIQGALHFFKDGWYWKFLNHRGSPLQGPFLTARTWPALPATLDSAFEDPQTKRVFFFSGRQMWVYTGKTVLGPRSLDKLGLGPEVTHVSGLLPRRLGKALLFSKGRVWRFDLKSQKVDPQSVIRVDKEFSGVPWNSHDIFQYQDKAYFCHGKFFWRVSFQNEVNKVDHEVNQVDDVGYVTYDLLQCP
  
Inhibitor
Name:
BDBM50116273
Synonyms:
CHEMBL306862 | N-(2-Aminomethyl-3H-benzoimidazol-5-yl)-2-benzyloxy-benzamide
Type:
Small organic molecule
Emp. Form.:
C22H20N4O2
Mol. Mass.:
372.4198
SMILES:
NCc1nc2ccc(NC(=O)c3ccccc3OCc3ccccc3)cc2[nH]1
Structure:
Search PDB for entries with ligand similarity: