Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50117237
Substrate
n/a
Meas. Tech.
ChEMBL_31413 (CHEMBL644556)
IC50
0.41±n/a nM
Citation
 Okamura, T; Kurogi, Y; Nishikawa, H; Hashimoto, K; Fujiwara, H; Nagao, Y 1,2,4-Triazolo[5,1-i]purine derivatives as highly potent and selective human adenosine A(3) receptor ligands. J Med Chem 45:3703-8 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50117237
Synonyms:
5,8-Diphenyl-3H-[1,2,4]triazolo[5,1-i]purine | CHEMBL330982
Type:
Small organic molecule
Emp. Form.:
C18H12N6
Mol. Mass.:
312.3281
SMILES:
c1nc2c(nc(-c3ccccc3)n3nc(nc23)-c2ccccc2)[nH]1
Structure:
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