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Target
G-protein coupled receptor 183
Ligand
BDBM50558426
Substrate
n/a
Meas. Tech.
ChEMBL_2063699 (CHEMBL4718952)
EC50
0.140±n/a nM
Citation
 Deng, X; Sun, S; Wu, J; Kuei, C; Joseph, V; Liu, C; Mani, NS Fluoro analogs of bioactive oxy-sterols: Synthesis of an EBI2 agonist with enhanced metabolic stability. Bioorg Med Chem Lett 26:4888-4891 (2016) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 183
Synonyms:
EBI2 | GP183_HUMAN | GPR183
Type:
PROTEIN
Mol. Mass.:
41245.79
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108311
Residue:
361
Sequence:
MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNGK
  
Inhibitor
Name:
BDBM50558426
Synonyms:
CHEMBL4788348
Type:
Small organic molecule
Emp. Form.:
C27H46O3
Mol. Mass.:
418.6523
SMILES:
[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)(C)O |r,t:10|
Structure:
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