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Target
Carbonic anhydrase 13
Ligand
BDBM50562972
Substrate
n/a
Meas. Tech.
ChEMBL_2081166 (CHEMBL4736957)
Ki
17±n/a nM
Citation
 Mboge, MY; Combs, J; Singh, S; Andring, J; Wolff, A; Tu, C; Zhang, Z; McKenna, R; Frost, SC Inhibition of Carbonic Anhydrase Using SLC-149: Support for a Noncatalytic Function of CAIX in Breast Cancer. J Med Chem 64:1713-1724 (2021) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII)
Type:
Enzyme
Mol. Mass.:
29445.78
Organism:
Homo sapiens (Human)
Description:
Q8N1Q1
Residue:
262
Sequence:
MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH
  
Inhibitor
Name:
BDBM50562972
Synonyms:
CHEMBL4799997
Type:
Small organic molecule
Emp. Form.:
C15H13F2N3O3S
Mol. Mass.:
353.344
SMILES:
NS(=O)(=O)c1ccc(cc1)N1CCN(C1=O)c1ccc(F)cc1F
Structure:
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