Reaction Details Report a problem with these data
Target
Neuropeptide FF receptor 1
Ligand
BDBM50565184
Substrate
n/a
Meas. Tech.
ChEMBL_2090999 (CHEMBL4772262)
Ki
25±n/a nM
Citation
 Nguyen, T; Marusich, J; Li, JX; Zhang, Y Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development. J Med Chem 63:12387-12402 (2020) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 1
Synonyms:
G-protein coupled receptor 147 | Gpr147 | NPFF1_RAT | Neuropeptide FF receptor 1 | Npff1 | Npffr1 | RFamide-related peptide receptor OT7T022
Type:
PROTEIN
Mol. Mass.:
48338.68
Organism:
Rattus norvegicus
Description:
ChEMBL_10681
Residue:
432
Sequence:
MEAEPSQPPNGSWPLGQNGSDVETSMATSLTFSSYYQHSSPVAAMFIAAYVLIFLLCMVGNTLVCFIVLKNRHMRTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALFTIAVIWALALLIMCPSAVTLTVTREEHHFMLDARNRSYPLYSCWEAWPEKGMRKVYTAVLFAHIYLVPLALIVVMYVRIARKLCQAPGPARDTEEAVAEGGRTSRRRARVVHMLVMVALFFTLSWLPLWVLLLLIDYGELSELQLHLLSVYAFPLAHWLAFFHSSANPIIYGYFNENFRRGFQAAFRAQLCWPPWAAHKQAYSERPNRLLRRRVVVDVQPSDSGLPSESGPSSGVPGPGRLPLRNGRVAHQDGPGEGPGCNHMPLTIPAWNI
  
Inhibitor
Name:
BDBM50565184
Synonyms:
CHEMBL4799458
Type:
Small organic molecule
Emp. Form.:
C11H11ClN4
Mol. Mass.:
234.685
SMILES:
Cc1cc(NC(N)=N)nc2ccc(Cl)cc12
Structure:
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