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Target
D(2) dopamine receptor
Ligand
BDBM50099814
Substrate
n/a
Meas. Tech.
ChEMBL_60053 (CHEMBL671368)
Ki
180±n/a nM
Citation
 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hübner, H; Gmeiner, P Stereocontrolled dopamine receptor binding and subtype selectivity of clebopride analogues synthesized from aspartic acid. Bioorg Med Chem Lett 13:3293-6 (2003) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50099814
Synonyms:
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide | 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-3-yl)-amide | CHEMBL298875
Type:
Small organic molecule
Emp. Form.:
C23H23BrN2O2
Mol. Mass.:
439.345
SMILES:
COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1
Structure:
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