Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 6
Ligand
BDBM50139789
Substrate
n/a
Meas. Tech.
ChEMBL_3609 (CHEMBL618092)
IC50
0.7±n/a nM
Citation
 Bondensgaard, K; Ankersen, M; Thøgersen, H; Hansen, BS; Wulff, BS; Bywater, RP Recognition of privileged structures by G-protein coupled receptors. J Med Chem 47:888-99 (2004) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
46968.43
Organism:
Homo sapiens (Human)
Description:
P50406
Residue:
440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN
  
Inhibitor
Name:
BDBM50139789
Synonyms:
CHEMBL353389 | {3-[2-(3-Bromo-phenyl)-1H-indol-3-yl]-propyl}-dimethyl-amine
Type:
Small organic molecule
Emp. Form.:
C19H21BrN2
Mol. Mass.:
357.287
SMILES:
CN(C)CCCc1c([nH]c2ccccc12)-c1cccc(Br)c1
Structure:
Search PDB for entries with ligand similarity: