Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM50139790
Substrate
n/a
Meas. Tech.
ChEMBL_106343 (CHEMBL713798)
IC50
612.0±n/a nM
Citation
 Bondensgaard, K; Ankersen, M; Thøgersen, H; Hansen, BS; Wulff, BS; Bywater, RP Recognition of privileged structures by G-protein coupled receptors. J Med Chem 47:888-99 (2004) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM50139790
Synonyms:
CHEMBL170530 | {5-[2-(4-Bromo-phenyl)-5-methyl-1H-indol-3-yl]-pentyl}-cyclohexyl-amine
Type:
Small organic molecule
Emp. Form.:
C26H33BrN2
Mol. Mass.:
453.458
SMILES:
Cc1ccc2[nH]c(c(CCCCCNC3CCCCC3)c2c1)-c1ccc(Br)cc1
Structure:
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