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Target
Melatonin receptor type 1A
Ligand
BDBM50140308
Substrate
n/a
Meas. Tech.
ChEBML_105100
Ki
0.130000±n/a nM
Citation
 Sun, LQ; Chen, J; Takaki, K; Johnson, G; Iben, L; Mahle, CD; Ryan, E; Xu, C Design and synthesis of benzoxazole derivatives as novel melatoninergic ligands. Bioorg Med Chem Lett 14:1197-200 (2004) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50140308
Synonyms:
CHEMBL18845 | N-{(1R,2R)-2-[2-(4-Phenyl-butyl)-2,3-dihydro-benzooxazol-7-yl]-cyclopropylmethyl}-isobutyramide
Type:
Small organic molecule
Emp. Form.:
C25H32N2O2
Mol. Mass.:
392.5338
SMILES:
CC(C)C(=O)NC[C@@H]1C[C@H]1c1cccc2NC(CCCCc3ccccc3)Oc12
Structure:
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